Printable Meeting FlierMarch Meeting Notice
Tuesday, March 24, 2009
The New Alphabet Soup: Achieving Optimum Selectivity and Resolution in Gas Chromatography
Dr. Nicholas H. Snow
Department of Chemistry and Biochemistry
Director of the Center for Academic Industry Partnership
Seton Hall University
South Orange, NJ
Abstract:
In the past decade or so, there has been a tremendous potential growth in the analytical capabilities of gas chromatography. A short list of new or improved systems includes (but is not limited to): the GC itself, GC-MS, GCxGC, GCxGC-MS and common sample preparation techniques associated with GC: HS, SPE, SPME, SBSE and LLE. These techniques may all be readily automated and validated for many applications using commercially available components. While instrumental capability has clearly increased, the fundamental problem of obtaining optimum resolution from the combined sample preparation and chromatographic method remains. From a chemistry point-of-view, the problem underlying resolution is selectivity. These “new” chromatographic and sample preparation techniques necessitate a new look at how and where selectivity is generated in the whole method. For examples, in moving from a traditional headspace extraction to a headspace-SPME extraction, the additional equilibrium step involved with adding the fiber to the vial certainly changes the profile of compounds extracted. Further, the addition of the second column in GCxGC necessitates a change in thinking about how much selectivity is needed in sample preparation and the addition of MS changes this even further. Using flavor and solvent analysis as examples, the fundamentals of obtaining selectivity and resolution will be discussed in light of our many new instrumental capabilities.
Note:
Even if you do not plan on eating, please pre-register with Sheree Gold at 610-485-3479.
A tour of the Center of Excellence will begin at 5:45 pm.
Click on the second flyer above for information on the appetizer, soup and salad, and dessert choices.
About the Speaker:
Nicholas H. Snow is Professor and Chair of the Department of Chemistry and Biochemistry and Director of the Center for Academic Industry Partnership at Seton Hall University, South Orange, NJ. His entire education from first grade through PhD was in the Commonwealth of Virginia. He holds a BS in Chemistry from the University of Virginia and a PhD from Virginia Tech where he worked under the Direction of Prof. Harold McNair on computer simulations of gas chromatographic retention. He performed postdoctoral work in forensic toxicology at the University of Virginia prior to his arrival at Seton Hall in 1994. Over the past 15 years he has published 45 research articles and book chapters on many aspects of separation science, most notably gas chromatography and sample preparation. His research group has active projects in fundamental gas chromatography, LCxGC, GCxGC, SPME, GC-MS and ion mobility spectrometry with application areas including drugs, solvents, flavors and fragrances. He is especially interested in broadening the classes of compounds amenable to GC and GC-MS analysis. He is a member of the Governing Board of the Eastern Analytical Symposium and was its President in 2001. He chaired Seton Hall’s university-wide Middle States re-accreditation in 2004 and he has been recognized twice by Seton Hall’s Board of Regents for outstanding teaching and service to students.
Details:
| Location: | Agilent Technologies |
| Times: | 5:00 PM Executive Committee Meeting 5:45 PM Social "Hour" 6:30 PM Dinner 7:30 PM Presentation |
| Cost: | $30 |
| Dinner Choices: | Buffet |
NOTICE TO STUDENTS AND FACULTY: Full-time students with valid ID may attend dinner meetings at half-price. Faculty members at colleges and universities are urged to bring one or more students to the meeting. If they do, they also can attend at half-price.