September Meeting Notice

Tuesday, September 26, 2006

Unifying Chromatography to Meet Business Needs

Thomas L. Chester

The Procter & Gamble Company, Cincinnati, OH 45241

Abstract:

Chromatographers often focus on their particular specialization, such as GC, HPLC, SFC, or preparative separations, even though the theory is very similar for all these techniques. In the workplace, the practice of chromatography has become highly empirical. We require specific methods be executed without deviation, and update old methods only with the fewest changes possible. Chromatographic responsibilities are assigned to entry-level employees who struggle to learn the proc-edures and record keeping, and have no time to develop in-depth technical expertise. When improvements are necessary, we focus on simple adaptations, and employ only empirical, univariate optimization methods.
But significant advantages are possible in selectivity control, speed of analysis, and overall costs. We need to take advantage of general chromatographic theory and move beyond perceived "rule-of-thumb" limits. In method development, we can take advantage of the complexity of parameter interactions, rather than changing one para-meter at a time. A unified theory of chromatography can combine these advantages for truly optimal chromatographic methods. This lecture will look at these possibilities, and discuss the progress made at Procter & Gamble utilizing HPLC multivariate optimization for meeting business needs. The potential for further improvements expanding beyond the current bounds of conventional HPLC will be detailed.

About the Speaker:

Tom Chester obtained a B.S. degree in chemistry from the Florida State University in 1971, and in 1976 obtained a Ph.D. degree in chemistry from the University of Florida, where he worked under the direction of J. D. Winefordner. He joined The Procter & Gamble Company in 1976 as a staff analytical chemist. There his research initially focused on meta-bolism, trace analysis and analytical applications of flames. Since 1982, he has focused on the development of supercritical fluid chromatography (SFC), unified chromatography, HPLC, and chromatography optimization. He is currently a Research Fellow in Procter & Gamble's Analytical Discovery Department. Tom received the 1993 Cincinnati Chemist of the Year award, from the Cincinnati Section of the ACS, and the Keene P. Dimick Award in Chromatography, presented at the 1994 Pittsburgh Conference. He is an Adjunct Professor of Chemistry at the University of Cincinnati.
Tom has authored or coauthored over 70 publications, all involving chromatography. He founded and continues as President of Supercritical Conferences, which presents international symposia in supercritical fluid techniques. Dr. Chester is on the editorial advisory boards of the Journal of Separation Science and The Journal of Liquid Chromatography, and previously served on the boards of the Journal of Microcolumn Separations, the Journal of Supercritical Fluids, the Instrument-ation Advisory Panel for Analytical Chemistry, and ASTM Committee E-19.12. He has served 17 years with the ACS Division of Analytical Chemistry, including Chair of the Subdivision of Chromatography and Separations Chemistry.

Details:

Location:
Times:	5:00 PM Executive Committee Meeting 5:45 PM Social "Hour" 6:30 PM Dinner 7:30 PM Presentation
Cost:	$30
Dinner Choices:	.

NOTICE TO STUDENTS AND FACULTY: Full-time students with valid ID may attend dinner meetings at half-price. Faculty members at colleges and universities are urged to bring one or more students to the meeting. If they do, they also can attend at half-price.