The Chromatography Forum

of Delaware Valley

Abstract:

Viral vectors are increasingly being used in clinical trials for gene therapy applications. Manufacturing of safe and efficacious clinical-grade virus relies on a scalable and cost-effective production process.  This presentation will cover resins and techniques used in the development of processes that can be used in the manufacturing of safe and efficacious clinical-grade virus.  We will cover novel affinity and ion exchange-based purification steps and step alternatives, including core bead technology and membrane formats.

Speaker Bio:

Tina has 38 years of experience in clinical research, assay development, and process development of biotherapeutic molecules.  She started doing clinical research at the Cardiovascular Center at New York Hospital in 1984 researching the Renin/Angiotensin System.  In 1998 she moved to Cytiva where, for the last 24 years, she has been helping customers develop scalable processes for the manufacture of biotherapeutics.